Thus says the LORD, the Redeemer of Israel and its Holy One, To the despised One, To the One abhorred by the nation, To the Servant of rulers, “Kings will see and arise, Princes will also bow down, Because of the LORD who is faithful, the Holy One of Israel who has chosen You.” (Isaiah 49:7)

despised, abhorred. This speaks to the humiliating treatment of the Servant at his first advent, a theme emphasized by Isaiah (50:6–9; 52:14–15; 53:3). The “nation” is used collectively for all who reject him, particularly Gentiles, who are the rulers, kings, and princes referred to as someday giving exalted treatment to the Servant at his second advent. Former oppressors will bow down to him as in 52:15, because of the salvation of Israel. (John MacArthur)

kings shall see and arise, princes also shall worship; they shall see the glory and majesty of Christ, and rise up in reverence of him, and fall down before him and worship him; which has had its accomplishment in part and will have a further fulfilment in the latter day. (Excerpt from John Gill’s Exposition of the Bible)